In summary, the vision was not affected by autoimmune phenomena or alterations in the behavior of ophthalmic cells due to the intravitreal injection of these nanoparticles.
Use of small molecule inhibitors such as carmustine (inhibitor of glutathione reductase) or dehydroepiandrosterone (inhibitor of G6PD) provide rapid alterations in the behavior of the redox enzymatic network, but this is potentially at the expense of specificity.
The oncogenesis of breast cancer involves multiple events, including genetic and epigenetic alterations in the behavior of normal and malignant cells, as well as other cells that interact with cancer cells [ 1].
Treatment of adult rats with phencyclidine (PCP), antagonist of NMDA glutamate receptors, used to mimic some signs and symptoms of schizophrenia, was followed by increased efflux of acetylcholine [ 40] and alterations in the behaviors modulated by muscarinic receptors [ 41].
As discussed above, incubation of PDC-109 with DMPC unilamellar vesicles leads to dramatic alteration in the aggregation behavior of various target proteins (Fig. 5A, S1A and S3A).
This alteration in the crimping behavior of collagen may thus contribute to the underlying tissue changes which culminate in fissures and annual tears in the degenerating disc.
The increase of the heating rate did not result in significant alterations in the thermal behavior of the samples.
Alterations in the elastic behavior of arteries is an early sign of vascular damage in atherogenesis and may be promoted by oxidative stress (OxS).
DNase pretreatment showed minor alterations in the sedimentation behavior of the proteins but these were within the margins of sample variability (Figure 2B).
Several mouse knockouts for these homeobox genes show changes in the fate of motoneurons, alterations in the migratory behavior of motoneurons, and defects in motor axon extension [24], [39], [40], [41].
