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Intensively managed annual cropping systems have produced high crop yields but have often produced significant ecosystem services alteration, in particular hydrologic regulation loss.
In order to correlate these changes to local alteration in particular cardiac regions, we dissected mouse hearts at P10 when changes were high.
Several studies have shown that high-fructose intake may lead to adverse metabolic alteration, in particular increase in plasma TG, hepatic insulin resistance, and liver steatosis [ 3, 25].
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The pathophysiology of sinus vein thrombosis (SVT) is still controversial in patients and experimental animals, the microcirculatory alterations in particular.
Unexpectedly, these changes did not correlate with histomorphological alterations, in particular with dilated ICS in esophageal mucosa.
Both inhibitors induce broadly the same morphological alterations, in particular changes in cell shape and formation of intracellular vesicles.
We found that chromatin alterations in particular histone methylation could act as persistence detector or irreversibility switch.
In many cases, the functional and hence clinical significance of the sequence alterations, in particular single-nucleotide variants (SNVs) outside coding regions, is uncertain.
The analysis of sarcomeric cytoskeleton alterations, in particular of the M-band, might provide important clues to understand the pathological mechanisms in DCM.
This finding is in contrast to the recently identified correlation between histopathological alterations, in particular basal cell hyperplasia, and elevated gene expression of desmosomal proteins [ 39].
Immune cytokines have overlapping functions and act synergistically with each other in a concerted manner, so that small alterations in particular combinations of cytokines can have larger effects.
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