Sentence examples for alteration in normal from inspiring English sources

Alteration in normal colonic pH and bacterial picture leads to incomplete release of drug from the designed delivery system.

Interestingly, some gene polymorphisms were associated with a lower methylation of the CpG islands examined, thus suggesting that genetic factors can influence this epigenetic alteration in normal colorectal mucosa [13].

However, whether this methylation-driven gene silencing mechanism represents a potential field effect due to an unidentified molecular alteration in normal mucosa or the expression of pre-existing multiple hyperplastic polyps from which CRC arises through the serrated pathway [38], as it has been recently suggested [32], remains unknown.

Moreover, alteration in normal growth factor responsiveness is a general hallmark of tumorigenesis in numerous cell types.

The presence of a mutation in the huntingtin (Htt ) gene causes alteration in normal cellular functions, through a gain or a loss of function of the protein.

On the other hand, CA100 produced antidiabetic action in streptozocin-induced mice, which might imply that the hypoglycemic nature of the lower dose would be apparent when there is an alteration in normal blood glucose regulatory systems by diabetes.

As suggested by Borsook et al. (2012), Migraine is associated with alterations in normal homeostatic mechanisms (e.g., altered sleep, abnormal autonomic function).

About: Detect rare or de novo copy number alterations in normal DNA samples.

Simon-Sanchez, J. et al. Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals.

Glioblastoma is the most common and deadly brain tumor, possibly arising from genetic and epigenetic alterations in normal astroglial cells.

AGE modification of proteins may lead to alterations in normal function by inducing cross-linking of extracellular matrices.