Sentence examples for alteration implicated in from inspiring English sources

Unlike chemotherapy, which indiscriminately kills fast-multiplying cells -- healthy ones as well as cancerous cells -- Herceptin focuses on a specific genetic alteration implicated in the cancer, and thus has relatively few side effects.

These data suggest that mutation of the p16INK4 gene is not a frequent genetic alteration implicated in prostate cancer development.

Looking for distinctive gene expression patterns in different brain cell types offers a more efficient way to search for genetic alterations implicated in autism and reveals a molecular signature of the disorder.

Somatic alterations implicated in cancer development and growth advantage are called driver mutations.

A better understanding of the critical alterations implicated in tumor initiation is necessary to reduce the mortality rates through early diagnosis and treatment.

154 Nevertheless, apart from activating mutations of KIT or PDFGRA, our understanding of fine molecular alterations implicated in GISTs pathogenesis are limited.

Many of these complications in generating biological context for proteomic alterations implicated in prostate cancer progression are being addressed through smaller-scale integrative approaches that correlate transcriptomic and proteomic experimental data, mine publicly available data sets, and add dimensionality through the inclusion of molecular interaction data.

To explore whether NORE1 alteration is implicated in colorectal tumorigenesis, we initially determined expression levels of NORE1 transcripts in 80 noncancerous tissues and 10 cancer cell lines using semi-quantitative RT-PCR analysis.

Recently, epigenetic alterations were implicated in valvular interstitial cell polarization.

Somatic VHL gene alterations are implicated in the pathogenesis of MEN2 pheochromocytomas.

Although surfactant alterations are implicated in the pathogenesis of ARDS, surfactant replacement remains of unproven benefit in adult patients.