The phrase "alteration has been reported" is correct and usable in written English.
It can be used in contexts where changes or modifications have been documented or communicated, often in formal or technical writing.
Example: "In the latest update, it was noted that an alteration has been reported in the project specifications."
Alternatives: "a change has been noted" or "modifications have been documented."
Collagen alteration has been reported as the primary explanation for skin aging and wrinkle formation (Jung et al. 2015).
Among these mechanisms, target alteration has been reported to be responsible for a high level of resistance to CIP whereas efflux pump and Qnr protein mediated mechanisms attributed to a low level of resistance (Jacoby 2005; Strahilevitz et al. 2009).
Recently, another alteration has been reported; gain of the distal part of chromosome arm 17q.
Histone acetylation is a known epigenetic mechanism of regulation of gene expression, and its alteration has been reported in many human cancers [ 83].
This alteration has been reported in different populations of Plutella xylostella, Plodia interpunctella, Heliothis virescens, and Spodoptera exigua and also for several Cry proteins (Cry1Aa, Cry1Ab, Cry1Ac, and Cry1Ca) [ 3].
Mitochondrial alteration has been reported in association with aging [ 27, 40]; however in these four patients, the number of CXO negative fibres is seen in higher proportion (2-32-3%xpected in aging process and three of patients were in their 60s.
However, some patients who initially respond the CLL eventually relapse because of the development of resistance, and presence of del(17p), especially in combination with other complex cytogenetic alterations, has been reported to predispose CLL patients for development of resistance9.
While an association between MSI and FHIT alterations has been reported by Huiping et al (2002), the relationship between Fhit and Mlh1 expression has not been previously studied in gastric carcinomas.
Reduced expression of LPS and alterations in LPS modification has been reported for intracellular Salmonella [41], [42], [43].
