These included seven genetically-diverse pancreatic cancer cell lines that together harbor the vast majority of copy number alterations from which the 185 genes were selected.
A third mineral, leucoxene, is an alteration of ilmenite from which a portion of the iron has been naturally leached.
The work may date from an 1893 interior alteration, for which Johnson used the architects Babb, Cook & Willard.
An initial set of 14,201 T3 SK lines were screened for alterations in trichome morphology, from which thirteen showed variation in cell shape, branch number, or the texture of the cell surface.
Gene expression of a tumor is a complex intermediate phenotype that is determined by many different factors: (1) the host genotype, (2) eventual somatic mutations and genomic alterations, (3) the cell from which the tumor originated, and (4) the specific microenvironment in terms of stroma cells, infiltrating cells and cell signaling molecules.
It is likely that the accuracy rates for any tumor-only pipeline will improve with increasing numbers of control/normal sample data from which germline alterations can be subtracted, and more importantly represent the same population distribution in which the primary analysis is carried out.
Following the latter consideration, we hypothesized that EC response to gravitational alteration could depend on the district from which the cell population derives and could be different in cells derived from macro- or microcirculation.
To provide the background from which disease-related alterations can be interpreted, we start with a summary of the principal features of gap junctions and connexin expression in the normal adult heart.
Both alterations were observed in the primary tumors from which these cell lines were established.
It is likely that the illite was either derived from hydrothermal alteration, which may be a precursor to frictional melting (Magloughlin 1992), or from the alteration of the pseudotachylyte matrix.
