The phrase "alteration frequency of" is correct and usable in written English.
It can be used in contexts related to changes or modifications occurring over a specific period or rate, often in scientific or technical discussions.
Example: "The alteration frequency of the genetic material was measured to understand the rate of mutations."
Alternatives: "rate of alteration" or "frequency of changes".
ERK and PI3K/AKT have been identified as the two most commonly altered pathways in prostate cancer with alteration frequency of 42 43 % in primary and 90 100 % in metastatic prostate cancer [ 148].
Pearson correlations were calculated by weighting the alteration frequency of each locus on a linear scale.
Furthermore, based on TCGA data integrated analysis, cumulative alteration frequency of TP63 (35 %), EGFR (23%%) and NFEL2 (19%%) were found to be higher than reported in COSMIC and cBioPortal, consistent with as described in other reports [ 4, 56].
These two closely located (within a 39.8 kb region at 10q24.1) candidate genes, showed alteration frequency of 57.5% with gain of gene copy number in Asian (Table 1A), whereas the alteration frequency was only 20% in Caucasian patients.
Although several genes involved in Wilms' tumour have been identified, as described above, the alteration frequencies of these genes (loci) and how many loci are altered in the tumour are still unknown.
In addition, parent-of-origin effect plays a major role in the genetic alteration frequencies of the pair of reciprocal hybrids, thus further implicating partitioning of epigenetic mechanisms in somaclonal variation, although which can be manifested as mainly genetic alterations.
Using the list of 1162 genes, the distributions of alteration frequencies for each genomic dimension or combination of dimensions were assessed.
GISTIC differs from these methods in that it assesses the statistical significance of the combination of alteration frequency and magnitude across the genome.
To determine hrHPV-specific chromosomal alterations, the frequency of alterations was compared between hrHPV-positive (12 HNSCCs and 10 CxSCCs) and hrHPV-negative tumours (30 HNSCCs) for all chromosomal regions.
The important finding may be the expression change of p85 showed the potential alteration of frequency of metastasis.
Surprisingly, difference in genetic alteration frequencies between the pair of reciprocal F1 hybrids is much greater than that between the two pure-line subspecies.
