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The phrase "alteration frequency and" is correct and usable in written English.
It can be used in contexts discussing changes or variations in frequency, particularly in scientific or technical writing.
Example: "The study focused on the alteration frequency and its impact on genetic diversity within the population."
Alternatives: "change rate and" or "modification frequency and".
Exact(2)
GISTIC differs from these methods in that it assesses the statistical significance of the combination of alteration frequency and magnitude across the genome.
Data on DDHD2 copy number alteration frequency and patient survival in patients with different cancer types was generated using cBio portal (http://www.cbioportal.org/public-portal/) [ 50].
Similar(58)
Alteration frequencies and frequency differences in MSS samples are shown in Figure 1.
We also found several candidate genes showing different alteration frequency between Asian and Caucasian patients, such as ARHGAP19 and FRAT2.
A significantly higher alteration frequency for RPN2 and HMGB1 genes was observed in CRC tumors, when compared with other tumors (Fig. 4b).
A significantly higher alteration frequency for RPN2 and HMGB1 was also observed in CRC tumors, compared to other eight common solid tumor types.
Most of the studies included >200 patients See also Fig. 3 for illustration (bar graph) FGF fibroblast growth factor aIncluded FGFs with alteration frequency ≥5 % and at least 5 cases with the alteration.
In addition, when tumors were grouped into two major NSCLC tumor subtypes, adenocarcinoma (ADC) and squamous cell carcinoma (SCC), six chromosomal imbalance regions showed difference of more than 50% in alteration frequency between ADC and SCC in Asian lung cancer patients (Table 2A).
ERK and PI3K/AKT have been identified as the two most commonly altered pathways in prostate cancer with alteration frequency of 42 43 % in primary and 90 100 % in metastatic prostate cancer [ 148].
Once we get the smoothed segments, we perform two independent analyses for each gene loci: a signal correlation analysis and an alteration frequency analysis.
Furthermore, based on TCGA data integrated analysis, cumulative alteration frequency of TP63 (35 %), EGFR (23%%) and NFEL2 (19%%) were found to be higher than reported in COSMIC and cBioPortal, consistent with as described in other reports [ 4, 56].
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