Sentence examples for alteration data to from inspiring English sources
For this analysis, we used the copy number alteration data to link unique genetic variants with epigenetic pathway status.
One of the most successful approaches to discerning the signal in mutation data or in copy number alteration data is to seek out those genes or regions which are altered at a frequency above a background random model.
The available patient information, clinical and gene alteration data relative to these samples are presented in Supplementary Table 1.
Towards this goal, we propose a network-based method to integrate copy number alteration data with human protein-protein interaction networks and pathway databases to identify pathways that are commonly disrupted in many different types of cancer.
This app is intended to help users easily investigate genomic alteration data in the context of biological networks.
We also find that highly expressed genes (with higher µ) tend to be explained better by copy number alteration data, both before and after normalization by standard deviation.
By classifying patients into more homogeneous tumor groups, genomic alteration data also might allow the enrichment of patient subpopulations with genetic targets that are more likely to respond to specific molecularly targeted therapy.
To identify oncogene candidates within the 9p13 region, we leveraged existing whole genome alteration data from OPLs and oral tumors and global gene expression data from oral tumors.
To view and analyze single nucleotide polymorphism (SNP) and comparative genomic hybridization (CGH) array alteration data tools and methods such as VAMP [ 27] and waviCGH [ 28] are options based on web technologies, whereas Genome Alteration Print [ 29] is a desktop application.
Sequence mutation and DNA copy number alteration data for all TCGA GBM cases was obtained from the TCGA data portal [48].
(1) More alteration data: the next phase of the TCGA GBM project will be sequencing over 6,000 gene and microRNA targets in several hundred additional GBM cases, as well as a number of tumor and paired normal complete genome sequences.
