LV hypertrophy and QT interval alterations coupled with decreased cardiac function are commonly observed with diabetes related CVD [ 10].
Indeed, a plethora of data indicates that psychological and immunological (particularly LPS) stressors promote marked hypothalamic neurochemical alterations, often coupled with signs of sickness (e.g. fever, piloerection, ptosis, curled body posture) or depressive-like symptoms, such as anhedonia [ 38, 40, 46- 49].
Ultimately, this study will evaluate whether alterations in endotoxin, coupled with altered metabolic profile, in type 2 diabetics might further explain the observed improvement in the clinical profiles of patients treated with these therapies.
But if the words were bland, the act of their alteration, however momentary, coupled with what happened just before and just after, left the stench of cover-up, federal prosecutors have argued.
This change in cytokine milieu, coupled with alteration in chemokines and chemokine receptor expression, can have a significant influence on the development and progression of arthritis, including AA, which is a Th1-mediated disease.
It was suggested that alteration in membrane architecture and function coupled with alterations in gene expression profiles may contribute to the observed beneficial impact of n−3 type polyunsaturated fatty acids on cognitive functions.
Therefore, reprogramming of cellular energy metabolism during tumorigenesis is expected to be coupled with alteration in nutrient-sensing and signaling pathway [ 5].
The framework where the wavelet analysis of copy number alteration based on expression coupled with the gene regulatory network analysis, provides a blueprint for leveraging genomic data to identify key regulatory components and gene targets.
Our previous evidence suggests that alterations in skeletal muscle lipid metabolism coupled with altered mitochondrial function may also develop.
Third, all miRNAs may not be able to result in phenotypic changes on their own; their effect may be context specific and may need to be coupled with alterations of expression of either other miRNAs or mRNAs to alter phenotype.
