The phrase "alteration at position" is correct and usable in written English.
It can be used in contexts such as programming, data analysis, or any situation where a specific change is being referenced at a particular location within a sequence or structure.
Example: "The alteration at position 5 in the array resulted in a significant change in the output."
Alternatives: "change at index" or "modification at location".
It involved an alteration at position 2685 (T>C) that resulted in a Tyr to His substitution at codon 856 (Y856H) in exon 11.
Correspondingly, the effect of the threonine substitution at position 392 on CXCR4 binding was much more severe than that of alteration at position 393.
In addition, the alteration at position 150 (138 in H3) from Ala to Ser, which may affect the conformation of residues lining the receptor binding site, has also been linked to changes in receptor specificity in H1 viruses [38].
To determine whether the newly identified sequence alteration at position 78 (US56) was responsible for the 2.2-fold increase in P97 promoter activity, site directed mutagenesis was performed.
The mutations in ura3 -1, ura3 -p, and ura3 -e are the following: G to A at position 701 of URA3, G-to-A change at position 608, and T-to-A alteration at position 170, respectively.
We identified a novel BRCA1 mutation in two Jewish-non-Ashkenazi families with ovarian cancer: a thymidine to guanidine alteration at position 3053, resulting in substitution of tyrosine at codon 1017 for a stop codon (Tyr1017Ter).
Amino acid comparison within this region among 1918NA, USSR77NA, Tex91NA, Kaw176NA and Duck80NA suggested that each alteration at positions 430, 432, 434, and 455 (USSR77 numberinging) or deletion at position 435 in the 1918 virus NA could determine the low-pH stability (Figure 3C).
Similarly, the substitutions of the hydroxyl and basic side chain in serine and lysine with aliphatic and an acidic amide side chain in glycine and glutamate in three isolates with different arrangement, suggest functional alteration at positions 234 and 235 on the enzyme, respectively.
Although the residue alterations at positions 1512 1526 and at position 1530 had minor impact on toxin efficacy, the exchange of hydrophobic Ile at position 1529 in DmNav1 to the Lys present in rNav1.2 largely impaired the toxin-channel interaction.
Alterations at R776 position giving rise to a different amino acid substitution (p.R776C) have also been described as somatic mutations and in conjunction with p.L858R [ 5, 31].
Strikingly, all of the proteins in this second subclade have sequence alterations at conserved positions in the sterol-binding site.
