The phrase "alteration and increased" is not correct as it stands and lacks clarity in written English.
It can be used in contexts where you are discussing changes that involve both alteration and an increase, but it needs to be part of a more complete and coherent sentence.
Example: "The alteration and increased funding for the project have led to significant improvements in its outcomes."
Alternatives: "modification and enhancement" or "change and growth".
The findings of the reported study presented that suilysin-positive strain could show toxin to produce functional alteration and increase the permeability of BBB; and Suilysin-negative strain might stimulate the production of proinflammatory cytokines resulting in alteration of BBB permeability [ 76, 77].
Concurrent decreases in DYNLL1 expression in carcinomas with low BRCA1 expression reduced genomic alterations and increased homology at lesions.
Osteoporosis is characterised by reduced mineral density and bone mass, microarchitecture alterations and increased skeletal fragility.
Numerous experimental studies demonstrated the deleterious effects of nitrogen reactive species accumulation in ischemic-reperfusion cerebral injury through depletion of energy, lipid peroxidation, protein nitrosylation, DNA alterations and increased permeability of the blood brain-barrier [19] [21].
Data in rats (24) demonstrate that preconception obesity brought about by overfeeding leads to obesity, metabolic alterations, and increased adipose tissue cellularity in the offspring.
Investigators in several clinical trials have reported that HES is associated with coagulation alterations and increased blood transfusion requirements [ 20, 21, 34].
When comparing gastric carcinoma harbouring EGFR alterations with carcinomas with normal EGFR status or copy number, we observed a significant association between EGFR structural alterations and increased tumour size.
However, endothelial barrier function alterations and increased vascular permeability might contribute to hastening tumor cell extravasation, causing progression to stages of greater malignancy, with heightened invasiveness and, in some cases, increased distant metastasis.
It is known that both hypoxia and consecutive hypoxia/reoxygenation can exert a variety of effects on tumor cell biology, including activation of pro-survival signal transduction pathways, aberrant genetic and epigenetic alterations, and increased tumor angiogenesis.
