Sentence examples for alteration and activation from inspiring English sources

It has recently been shown that H2O2 is directly responsible for disulfide bond formation, which results in a conformational alteration and activation of ATM [29].

Fas ligand (FasL) expression, cell cycle alteration, and activation of c-Myc through the ERK pathway are reportedly involved in nickel-induced apoptosis (35, 36).

We have shown [17], [18], [20] that morphological alterations and activation of RhoA strongly affect ENaC activity by promoting trafficking of the channel to the plasma membrane.

Genetic alterations and activation of bypass tracks are two main mechanisms of acquiring resistance.

Thermal injury is associated with profound immunologic alterations and activation of the complement system [ 45].

To date, alterations and activation of the PI3K/AKT pathway are well established in the initiation and progression of extracranial human BC [ 6, 8- 14, 15, 15].

Lung cancer that develops in the absence of significant tobacco-smoke exposure appears to be a unique disease entity with novel genomic and epigenomic alterations and activation of molecular pathways that are not generally seen in tobacco-smoke-induced lung cancer.

As the intensive study of cell and molecular mechanism, gene alteration and abnormal activation have been revealed in the drug-surviving cancer cells.

The link between Drp1-mediated mitochondrial alteration and PKR activation remains to be investigated.

Furthermore, ROS can promote inflammation, alteration of vasomotion and activation of matrix metalloproteinases, thus causing platelet aggregation and stimulation of vascular smooth muscle proliferation [ 53, 54].

Septic patients with impaired cardiac function demonstrate inflammatory alterations and PARP activation.