The phrase "alter the tissue" is correct and usable in written English.
It can be used in contexts related to biology, medicine, or materials science, where changes to tissue structure or composition are discussed.
Example: "The researchers aimed to alter the tissue to improve its regenerative capabilities."
Alternatives: "modify the tissue" or "change the tissue".
Since prodrugs might alter the tissue distribution, efficacy and the toxicity of the parent drug, prodrug design should be considered at the early stages of preclinical development.
Interactions between pathogens and cells of the immune response can be modified by changes in their environment, such as suppression of the flow of blood and lymph, and, particularly in the case of the meninges, with their unsupported membranes, invasive dissection can alter the tissue architecture.
In the case of mechanical stimuli, the cells within the subjected tissue undergo a few aspects of the mechanical stimulus, and decide to alter the tissue matrix in a pertinent manner depending upon the aptness of stimulus.
Secretion of a broad range of bioactive molecules which alter the tissue microenvironment is now believed to be the main mechanism by which MSCs achieve their therapeutic effect.
Naturally mummified individuals are more suitable for bacterial DNA studies because they have not been impacted by any processes such as embalming that would alter the tissue environment [42].
Specifically, phonotrauma can (1) alter the tissue's physical properties by disrupting intracellular adhesion [1], and (2) modulate the tissue's cellular/molecular responses by altering gene expression [3].
Thus, IVCM offers a unique method to study corneal nerve alterations in a myriad of conditions, such as ocular and systemic diseases and following corneal surgery, without altering the tissue microenvironment.
As discussed above, smoking contributes to lung cancer evolution by both increasing mutation frequency as well as by altering the tissue environment to increase selection for adaptive oncogenic mutations.
Taken together, results suggest that the extract of Pancratium illyricum may act as antifungal agent both directly on the yeast growth and by altering the tissue invasion process.
I have found that the sunlight-similar straylight conditions used in the ICM set up for imaging and bleaching is the method of choice not altering the tissue integrity "on stage" over long periods of time (review in 4).
However, it is likely that these conditions alter the local tissue environment that controls the excitability of cardiac tissue and the neurons innervating it.
