Sentence examples for alter the targeting from inspiring English sources

By affecting the association of the C subunit with regulatory subunits in vivo, methylation is predicted to alter the targeting of PP2A to certain substrates and, as a consequence, potentially impact a wide range of signalling pathways [26].

We included these constructs in our study since the presence of the 5'-UTR may alter the targeting of proteins [ 34].

In plants, it has been reported that either a combination of 5' deletion and 3' uridylation of miRNA, or RNA editing events, alter the targeting and preference of Argonaute association [ 30].

During the shoot out, Paxton manages to lock the firing sequence — fortunately, Tucker has altered the targeting, and the beam misses.

For instance, altering the targeting subunit of the phosphatase PP1 leads to either an obese insulin resistant phenotype [53] or a normal phenotype depending on the donor background [54] even though both studies backcrossed onto the C57Bl/6 line.

Ashwell et al. have used computational redesign to alter the target-site specificity of the I-MsoI homing endonuclease, while maintaining wild-type binding affinity.

Entrepreneurs may discover at any point on the milestone path a need to redesign the product or alter the target market.

It is further shown that these perturbations can alter the target yields in a significant way, increasing the amount of 252Cf produced per unit curium consumption by over 40%.

On successful execution, SMR should alter the target cloud service/CSI/PSSA in an intended way.

The goal is to find molecules that bind with and alter the target's behavior and could be the basis for future drugs.

Because it is very likely that non-physiological levels of miRNAs will alter the target field, i.e. the specific set of mRNAs targeted, a more accurate measure of miRNA effects requires endogenous determinations.