Sentence examples for alter the specificity of from inspiring English sources

A second series of reporters, activated by human rhinovirus 3C protease, demonstrated that we could alter the specificity of the reporter by reengineering the protease recognition sequence.

Variations in N-CAM activity thus do not occur by changes in the amino acid sequence that alter the specificity of binding.

Conversely, ORC-binding could alter the specificity of Hat1p to modify substrates different from free histone H4.

The amino acid positions which vary only in certain subgroups and alter the specificity of a protein are called the Specificity determining positions (SDP's).

It is not possible without experiments to determine whether this amino acid substitution will alter the specificity of the RFs in question.

A mutation at amino acid 482 is known to alter the specificity of BCRP for its substrates (Honjo et al, 2001).

Modification in the structure of SAHA altered the specificity of 'δ ' towards a specific HDAC enzyme[83].

A PBP added to an in vitro assay altered the specificity of a moth pheromone receptor, making its response more specific [31].

The flexibility of the described design allows for sensor specificity change through altering the specificity of the aptamer.

Thus, the levQE170A/F292S mutations altered the specificity of the signaling complex independently of LevT.

Several groups reported success in altering the specificity of Type IIG REases.