Sentence examples for alter the propensity from inspiring English sources

Thus, the flanking sequence of the polyglutamine region does not simply alter the propensity to form a polyglutamine aggregate, but can directly affect its aggregation rate and responses, the subcellular localization of the inclusions, and the biochemical characteristics of the aggregates.

Cyclin D acts via TGF-β-Smad signaling to alter the propensity for endoderm versus neuroectoderm fate.

There have been some successful attempts to alter the propensity of MuLV for T-cell lymphomas by using an EμMyc transgenic mouse, which results in predominantly B-cell lymphomas [231], and by expressing platelet derived growth factor B-chain (PDGFβ) from an MuLV-based retrovirus to generate mice with glioblastomas, which require activation of PDGF receptors for tumourigenesis [219].

Time has not altered the propensity of some in the church to attack Islam; only these days censure is just as likely to come from a small but significant number of black majority church leaders.

Previous studies examining TREM2-triggered phagocytosis had not examined whether prior cell activation altered the propensity of TREM2 to regulate microglial phagocytosis.

Accordingly, deletion in the C-terminal domain of PACAP reduces drastically the binding affinity without altering the propensity of the analogues to activate the receptor at high concentration (Bourgault et al., 2008b).

Second, a single CNG (HmCNG) locus is present in the genome sequence of H. magnipapillata and the expression of this gene is tightly correlated with that of opsin [ 12], thus diminishing the possibility that our drug treatment differentially affected some other unknown, non-phototransductive CNG-based process that indirectly alters the propensity for cnidocyte discharge.

To study the association between antibiotic intake in pregnancy and the development of otitis media and placement of ventilation tubes (VTs) in the offspring under the hypothesis that antibiotics in pregnancy may alter the offspring's propensity for disease.

Point mutations in the TNF TM span reduce or enhance sensitivity to cotransin, depending upon whether the mutation increases hydrophobicity or alter the predicted helical propensity of the TM span.

Observed substitution patterns indicate that probable changes in local hydrophobicity are instrumental in altering the aggregation propensity of the peptide.

We end by proposing a set of mutations altering the swapping propensities, whose experimental characterization would contribute to refine our in silico derived hypotheses.