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And if it does happen, it could drastically alter the positioning of some of the top players currently operating, including Square, PayPal and many more.
Such a change could alter the positioning and the binding of a ligand within the ligand-binding pocket.
Both of these alternative DNA structures display changes in helical parameters that will alter the positioning of minor groove functional groups (Sinden 1994).
The inducer-mediated conformational change in the Keap1 structure may alter the positioning of Nrf2 relative to the E2-ubiquitination machinery such that Nrf2 can no longer be ubiquitinated and/or degraded by the Keap1 complex (Fig. 6B).
Together with previous data showing that inducers cause conformational changes in Keap1 without dissociation of Nrf2 [ 16– 18], these findings suggest that the inducer-mediated cysteine modifications of Keap1 may alter the positioning of Nrf2 relative to the E2-ubiqitination machinery such that Nrf2 can no longer be ubiquitinated and released from Keap1.
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The leucine104 is located only 4 Å from glutamic acid 334; replacing it by a large, positively charged arginine would alter the position of site II.
I don't believe anything is going to happen that will materially alter the position these people find themselves in.
"That is a significant difference and it is unlikely that any adjustment to the final figures will alter the position of the two countries".
The League Managers Association condemned Pardew's reaction and the chief executive, Richard Bevan, revealed that the organisation has been in discussions to alter the position of touchline technical areas to take managers further away from the action.
It is seen that the flow fields significantly alter the position and morphology of the dendrites.
Skiving can alter the position of the intended hole or result in damage to surrounding tissues.
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