The phrase "alter the phenotype" is correct and usable in written English.
It can be used in contexts related to biology, genetics, or any discussion about changing observable traits in an organism.
Example: "Researchers are exploring ways to alter the phenotype of plants to improve their resistance to drought."
Alternatives: "modify the phenotype" or "change the phenotype.".
The results showed that polyelectrolyte multilayers neither induce cytotoxic effects nor alter the phenotype of the endothelial cells.
Hemophilia A is an attractive gene therapy candidate because even small increases in FVIII levels will positively alter the phenotype.
Out of 1728 full-length clones we isolated 82 for their ability to alter the phenotype of tadpoles and/or the expression of Xbra and Xmyf-5.
Despite whole-genome sequencing, the roles of many gene products in fungi remain unknown, in part because gene deletion may not alter the phenotype when more than one paralog exists in the genome.
Loading T cells with AuNPs had no immediate effect on T cell viability as determined by Annexin-V/7-AAD staining (Figure 2a) and did not alter the phenotype of the cells (Figure S2 in Additional file 1).
CpG ODN also alter the phenotype of target malignant B cells as indicated by upregulation of MHC, immunostimulatory molecules, and antigens that serve as targets for other approaches to lymphoma immunotherapy such as CD20.
Therefore, we hypothesized that isolated and combined treatments of cyclic tension and transforming growth factor-β1 would alter the phenotype and subsequent collagen biosynthesis of aortic valve interstitial cells in situ.
Since P19 ES cells are pluripotent and respond to external stimuli that have the potential to alter the phenotype and thus its stemness, other cell types used in RNA silencing studies do not display the obvious effect and therefore, may affect experiments in subtle ways that would go undetected.
GM-CSF also appeared to alter the phenotype of dual functional CD8+ T cells in the lung.
Large-scale genetic changes induced by polyploidy are thought to influence the transcriptome, metabolome and proteome, which can concomitantly alter the phenotype and ecology of the individuals.
None of the other variants are coding variants, but thorough functional characterization is warranted to eliminate other mechanisms in which these variants might alter the phenotype.
