Sentence examples for alter the extracellular from inspiring English sources

Future studies should also examine the performance of 18F-FLT compared to 18F-FDG in monitoring the effect of treatment, particularly steroid therapy, which can alter the extracellular and intracellular glucose metabolism and affect 18F-FDG uptake.

We demonstrated that antibody-targeted ECM-derived peptides alone can be used to sufficiently alter the extracellular matrix microenvironment to induce a dramatic angiogenic response in the myocardial infarct area.

All lin-12 alleles that display genetic interactions with sel-1 and sel-11 [15] [16], [16] carry mutations that alter the extracellular domain, which would be positioned in the ER lumen during protein synthesis and folding [24], [25].

As mentioned in RESULTS, all of the lin-12 alleles used in this study carry missense mutations that alter the extracellular domain and cause constitutive LIN-12 activity; in some cases, the lin-12 alleles are composites of such activating mutations combined with second-site revertants that lower lin-12 activity.

This has recently been suggested to aid in enhanced chemotherapeutic efficacy in cancers pretreated to alter the extracellular matrix.

How do the effects of TNFα and IL-1β combine to alter the extracellular matrix of discs?

Other products, such as sorbitol, diacylglycerol, and fructose-6-phosphate, which are formed because of chronic hyperglycemia, also lead to basement membrane alteration by altering the extracellular matrix proteins.

In addition, quercetin reduced cancer progression by altering the extracellular catabolism of nucleotides in T24 cells (Rockenbach et al, 2013).

The stroma also plays a role in promoting angiogenesis, and altering the extracellular matrix, as well as increasing inflammatory cell recruitment to the area [ 21- 23].

Does altering the extracellular environment of a cancer cell have the same effect on metabolism and oxidative stress as detaching cells?

In accordance with these reports, we showed that acetate induces apoptosis in HCT-15 and RKO cells without altering the extracellular pH (complete medium).