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The phrase "alter the effectiveness of" is correct and usable in written English.
It can be used when discussing changes that impact how well something works or performs.
Example: "The new policy may alter the effectiveness of our current marketing strategy."
Alternatives: "change the efficacy of" or "affect the performance of".
Exact(26)
Burdens alter the effectiveness of public programs by restricting whether benefits reach their target population.
This variation may alter the effectiveness of NBS programs by location of birth.
Women and men also have different skillsets and areas of expertise which, if utilised correctly, can alter the effectiveness of humanitarian responses and overall community resilience.
"This novel insight points to broader norms, market failures or institutional constraints that alter the effectiveness of these resources for women," the report says.
Our data suggest that long hair and clothing, which cover the neck, do not alter the effectiveness of cervical collar immobilization as measured by the cervical ROM device.
Despite the fact that life events such as marriage, divorce and the death of a spouse can significantly alter the effectiveness of a will, many people have never updated their wishes, with a third of people admitting they simply haven't got round to it.
Similar(34)
This study was performed to determine whether this mutation altered the effectiveness of the adjacent splice site.
Previous research suggested that variable expression levels of the mammalian kinesin-13, MCAK, altered the effectiveness of anti-MT drugs on human cancer cells [9].
Second, the different delivery methods used may have resulted in varying concentrations of surfactant reaching the damaged alveoli and altering the effectiveness of therapy.
Increased population pressure and human activities have significantly altered the effectiveness of functions of ecosystems ("ecosystem services") at the local and regional scale.
Note that one way in which these host characteristics may contribute to variability is by altering the effectiveness of physiological control mechanisms at individual events in the pathway.
More suggestions(15)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com