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The phrase "alter the effectiveness" is correct and usable in written English.
You can use it when discussing changes that impact how effective something is, such as a strategy, method, or tool.
Example: "The new policy may alter the effectiveness of our current marketing strategy."
Alternatives: "change the efficacy" or "modify the impact".
Exact(26)
Women and men also have different skillsets and areas of expertise which, if utilised correctly, can alter the effectiveness of humanitarian responses and overall community resilience.
"This novel insight points to broader norms, market failures or institutional constraints that alter the effectiveness of these resources for women," the report says.
Despite the fact that life events such as marriage, divorce and the death of a spouse can significantly alter the effectiveness of a will, many people have never updated their wishes, with a third of people admitting they simply haven't got round to it.
Zinc experts say that many over-the-counter zinc products may not be as effective as those studied by researchers because commercial lozenges and syrups often are made with different formulations of zinc and various flavors and binders that can alter the effectiveness of the treatment.
Reduction of the dose by half (Experiment 3) did not alter the effectiveness.
Our data suggest that long hair and clothing, which cover the neck, do not alter the effectiveness of cervical collar immobilization as measured by the cervical ROM device.
Similar(34)
This study was performed to determine whether this mutation altered the effectiveness of the adjacent splice site.
Previous research suggested that variable expression levels of the mammalian kinesin-13, MCAK, altered the effectiveness of anti-MT drugs on human cancer cells [9].
It alters the effectiveness and biodistribution of the associated material and often can be correlated with resulting toxicity.
Second, the different delivery methods used may have resulted in varying concentrations of surfactant reaching the damaged alveoli and altering the effectiveness of therapy.
Note that one way in which these host characteristics may contribute to variability is by altering the effectiveness of physiological control mechanisms at individual events in the pathway.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com