Sentence examples for alter the coordination of from inspiring English sources

Positioned adjacent to amino acids that contribute to the iron coordination environment, substitutions at these locations (p.Gly195Arg and p.Ile224Ser) will influence their amino acid neighbours and alter the coordination of the iron atom(s).

Some other changes are in genes commonly observed to acquire substitutions during adaptation (the tail fiber gene 17 and the minor capsid gene 10B), or affect functions that may plausibly be argued to alter the coordination of life cycle components (DNA and RNA metabolism).

Taken together, it is possible that sirtuin proteins regulate the cell's metabolic status and physiology, which further alters the coordination of specific behaviors.

A total of 40 PHI-base mutations, including 16 bacterial, 21 fungal, 2 protozoan and 1 nematode PHI-base entries, altered the coordination of pathogen growth, disrupting this balance with the host organism, causing hypervirulence.

Redesign of the exterior of TRIL23C based on a biologically relevant recognition sequence found in GCN4, did not alter the coordination chemistry of [AuCl PEt3)].

Further this change should not alter the coordination chemistry as it retains the essential chemical feature of site 4, a hydroxyl that can contribute to the coordination shell of the permeant ion [31] (Figure 2C).

On the basis of these observations we conclude that FbpABp is unable to remove Fe3+ from a ferric xeno-siderophore or detectably alter the first coordination shell of Fe3+ under the in vitro conditions used.

Abolishment of these interactions would break the ChIN into smaller disconnected components and consequently alter the global coordination among distant genes, as in the case of HIST1 clusters.

Recently, we succeeded in altering the first coordination sphere of the diiron site in DcrH-Hr by replacing residue Ile119 located close to the exogenous ligand binding site with a Glu residue.

The resulting phosphodiester bond alters the coordination state of the catalytic Mg2+, hastening its dissociation and its replacement with Na+.

The obtained results show that mutations alter the flexibility and the coordination properties of the native state, with a specific impact on the dynamics of the α2-α3 hairpin hairpin, which in turn modify the protein interactive surface impinging on the binding sites for conversion inhibitors and activating the interacting properties of the β2-α2 loop [Figure 6].