Sentence examples for alter the active from inspiring English sources
Molecular models of this mutated protein showed that this mutation does neither alter the active site of α-galactosidase A nor interfere with the enzyme catalytic activity, but it could alter the enzyme stability [ 21].
As with skeletal muscle, changes in length alter the active force by varying the degree of overlap of the thick myosin and thin actin filaments.
These structures reveal, in particular, that this first mutation does not alter the active site.
Functional and structural lesions of ureteral endings seem to alter the active valve mechanism of the ureterovesical junction, causing vesicoureteral reflux.
Our simulations also predict that changes in inputs to the CPG that are not strong enough to destroy an ongoing rhythm will alter the active phase durations of the hip MN that is dominant in that rhythm and of the knee extensor MN while leaving the other hip MN activity period almost entirely unchanged, and that these changes are controlled by the excitatory INs in the CPG.
More recently, fascinating insights from X-ray crystallographic studies have indicated that there may be rare (hidden) conformations and sub-states that critically alter the active site environment for catalysis [20].
Ubiquitination of caspase-3 reduces activity of caspase-3 by altering the active site while also targeting the enzyme for proteasomal degradation.
It was found that adding the Co(Ni) citrate to Co2Mo10/Al2O3 catalyst significantly altered the active phase morphology.
Irreversible inhibitors are generally specific for one class of enzyme and do not inactivate all proteins; they do not function by destroying protein structure but by specifically altering the active site of their target.
Moreover, antibiotics altered the active fraction of enzymes controlling the thickness, composition and consistency of the mucin glycans.
Finally, our data support the hypothesis that antibiotic therapy additionally altered the active fraction of enzymes controlling the thickness, composition and consistency of the mucin glycans.
