The phrase "alter the activation of" is correct and usable in written English.
It can be used in contexts related to changing or modifying the state or function of something, often in scientific or technical discussions.
Example: "The new drug is designed to alter the activation of specific receptors in the brain."
Alternatives: "modify the activation of" or "change the activation of".
Interference with the ERK1/2 cascade with PD98059 did not alter the activation of moesin (Fig. 4B C).
The aim of the present study was to determine whether modulation of the parasite load within a certain period of time can in fact alter the activation of effector/protective CD8+ T cells.
In addition, ActRIIB treatment of immobilized mice also did not alter the activation of Smad2 or Smad3 (Fig. 2A).
Furthermore, treatment with siRIP3 did not alter the activation of caspase-8, but instead increased activation of caspase-9 and promoted endonuclease G translocation into OHC nuclei.
These findings suggest that arsenic exposure may alter the activation of CD4 T cells resulting in reduced cytokine secretion and immune suppression.
The results indicate that MEKK1, MEKK2 and MEKK3 deficiency do not alter the activation of JNK, p38 or ERK in IL-1β-stimulated FLSs.
These alterations could have modified the activity of receptors in cell membranes, thus altering the activation of intracellular pathways and downstream regulatory proteins, such as those related to the IGF-1/PI3-K/Akt/mTOR pathway, which are compartmentalized and activated through their translocation to the plasma membrane [ 52].
Vitamin D3 upregulated protein-1 regulates proliferative signaling during liver regeneration by altering the activation of genes involved in the extracellular signal-regulated kinase 1/2 and AKT signaling pathways (Kwon et al., 2011).
Calcium can also mediate apoptosis by altering the activation of cell surface death receptors and caspases.
Studies have confirmed that supplemental Zn2+ beyond or below certain critical dose produced negative effect on wound healing by altering the activation of nuclear transcription factors to increase the production of pro-inflammatory cytokines leading to immunosuppression [ 30].
These include modulation of nerves in larger airways by neurotrophins generated within diseased lung parenchyma, mechanical lung distortion from fibrosis altering the activation of cough receptors and gastro-oesophageal reflux disease (GORD), which is known to be present in approximately 80% of patients with IPF[ 4].
