Sentence examples for alter protein function from inspiring English sources

Mutation and domain shuffling together with other genetic events can create functional variation and in some cases completely alter protein function.

PTMs alter protein function by introducing structural changes through the addition or removal of covalently-attached functional groups on the amino acid chain.

This induces the irreversible formation of advanced glycation end products (AGE), which may alter protein function and protein degradation.

Increasing attention has been focused on oxidative modifications due to the crucial role of oxidative stress in aging, in addition to the fact that this type of modification is irreversible and may alter protein function.

A major challenge is to define how certain reactive intermediates may chemically modify critical proteins and how modification of specific amino acids may alter protein function which in turn may affect cell signalling, regulation, defence, function and viability.

For example, transfer of DNA from mitochondria to the nuclear genome can generate novel exons that alter protein function [22].

However, all CFC mutations which have been biochemically characterized alter protein function to some extent ([18], [26]; Rauen, unpublished data).

One of the coding variants, M225I, was identified in the synaptic vesicle gene DOC2A and was predicted to alter protein function.

Can changes in conformational flexibility alter protein function?

Frameshift mutations as well as missense mutations are known to alter protein function.

Of particular interest are non-synonymous SNPs, which may alter protein function and phenotype.