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The panel scanned every single autoradiogram and compared them with each other using image-processing software to alter orientation, intensity, and contrast.
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Simulations of hybrid DFT methods did not show that deuterium replacements alter orientations of 2- and 6-nitro with respect to phenyl ring, considering a larger size of the methyl group.
Electron microscopical examination revealed alterations in axonal cytoskeleton, altered orientation of microtubules (MT) and severe decrease in identifiable MT profiles in myelinated, and to a lesser extent, in unmyelinated fibers, as compared with control axons.
The potential of mean force (PMF) profiles of amino acids revealed qualitative differences, resulting into altered orientation and the choice of preferential interacting site with the metal surface.
This altered orientation may be responsible for juxtaposition of haem in a way so as to produce unusual γ-regioselectivity for the haem degradation reaction.
When goggle rearing (GR) started at P16-P30, 2 weeks of GR induced a marked over-representation of the exposed orientation, and 2 more weeks of GR consolidated the altered orientation maps.
The PSA-NCAM staining revealed that the Ts1Cje neuroblasts were reduced in number, but directional pattern of migration appeared normal and there was no obvious defects such as blockages or altered orientation.
We hypothesize that the P5 suppressor mutant, Pbs2(P584L) contains a G α-helix that is extended by one amino acid and forms a structure that is not optimal for YopJ inhibition because it alters orientation of the YopJ binding site in Pbs2 and, as a result, we observe the P5 suppressor mutant is inefficiently acetylated by YopJ.
The E4 allele can promote domain interactions through the altered orientation of Arg61 in the N-terminal domain.
The box was rotated back and forth between trials of repeated orientation to match the amount of motion perceived before trials of repeated and altered orientation.
Various mutation clusters destabilizing or altering orientation of regions of the protein predicted to contribute structurally to the maintenance of autoinhibition were identified.
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