The phrase "alter leading to" is not correct and does not convey a clear meaning in written English.
It may be intended to describe a change that results in a specific outcome, but the wording is awkward and unclear.
Example: "The changes in the policy could alter leading to unexpected consequences."
Alternatives: "change resulting in" or "modification causing".
The migratory properties of DCs seem to be altered, leading to sequestration in tissue and/or secondary lymphoid organs due to an alteration of chemokine receptor membrane expression and maturation.
Moreover, the PPV distribution around a tunnel can be altered, leading to high and low PPV zones around the tunnel.
In heart failure, the crosstalk between the endoplasmic sarcoplasmic reticulum (ER/SR) and juxtaposed mitochondria is altered, leading to malfunction of cardiomyocytes and decline of cardiac function.
When this excess water is managed using stormwater drainage systems, flow and water quality regimes of urban streams are severely altered, leading to the degradation of their ecosystems.
Both leaky activation of BMP signaling and accumulation of BMP BMPRI at the cell membrane are seen in FOP cells, suggesting possible aberrant association with FKBP12 in FOP.77 The most likely possibility is that FKBP12 interactions with the GS domain become altered, leading to promiscuous ACVR1/ALK2 activity.
3. The overall pattern of pesticides applied to the particular crop may have been altered, leading to different exposure to pesticide residues overall".
A direct effect will happen if the structural gene (pro-smtg) of TGase zymogen is altered, leading to the change in the specific activity of the protein.
Sometimes, the classical course of CT may be altered leading to a longer duration of symptoms and greater functional impairment [74].
When TiO2 nanoparticles are added to this polymeric material, the surface morphology is altered, leading to the formation of a sponge-like layer covering the stone substrate (Fig. 5b d).
"Daily hormone schedules are altered, leading to changes in hormones and thus changes in periods".
