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Although the role of Notch3 in the development of age-related cerebral small vessel disease can easily be envisioned, it remains speculative how the described mutations alter its function.
Now drugs can be developed for every protein to alter its function and help clear up a malfunction.
Any word class may alter its function in this way: the ins and outs (prepositions becoming nouns), no buts (conjunction becoming noun).
They have started the hunt for molecules that will alter its function, and are also analysing a set of substances that inactivate MarA.Initially, the researchers saw controlling the Mar regulon as a means to increase or restore the potency of existing antibiotics.
GDM is an ansamycin antibiotic, which has the ability to bind with Hsp90 (heat shock protein 90) and alter its function.
It should be noted that the alterations visible on the coach today may be merely the last in a sequence of changes made to refurbish worn or shabby components, to bring the coach up to date with changes in fashion, or to alter its function for new uses.
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The Beeson scholarship will support him as he extracts the enzyme from human brain samples to determine which structural changes alter its functioning.
Using the tyrosine residue may cause problems associated with labelling including nonspecific or poor binding, in vivo instability of the complex, and unwanted alterations to the peptide structure, such as the cleaving of internal disulphide bonds, which can alter its functioning [ 8 ].
Even though the overall structural organization of the p110β RBD is conserved (Zhang et al., 2011), we speculated that because we cannot detect any interaction with RAS, it might have lost or altered its function.
This article introduces a new method for generating benchmarks that is based on structural modifications of a user-specified design without altering its function.
Grooming in the form of fur-combing is generally considered the primary fur-combing isrigenerallye of the lemuriform toothconsideredsubsequenthehanges in morprimary across multiple lineages have altered its function and original its orolenal functiof.
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