The phrase "alter directly" is correct and usable in written English.
It can be used when referring to making immediate changes or modifications to something without any intermediaries.
Example: "To improve the system's performance, we need to alter directly the configuration settings."
Alternatives: "modify immediately" or "change directly".
Thus, Hdac1 or Hdac2 enteroid deficiency may alter directly or indirectly the production of endogenous inhibitors, which could maintain HDAC activity.
Neurologic complications may alter directly the outcome, increasing mortality and morbidity or indirectly by contraindicating early cardiac surgery.
Based on these studies, it is tempting to hypothesize that androgens may induce relaxation of myometrium via direct interaction with the membrane proteolipidic structure, which might alter directly or indirectly the function of gap junction channels; however, more evidence in needed.
Similarly, the reduction of the overall process of PSII photochemistry and electron transport activity, shown by the decrease in PI parameter value, indicated that both NiO-NPs and NiO-Bulk were able to alter directly the photosynthetic performance of L. gibba plant.
If elevated levels of IEG proteins in Tc1 mice are a protective response to elevated levels of oxidative stress, they may be a compensatory response in Tc1 (and DS) and not an abnormality that would be beneficial to alter directly with pharmacotherapies.
These experiments provide extremely strong evidence that position 84 of bird SWS (short wave sensitive) opsin would change color sensitivity of the organism, if the amino acid could be altered directly in an animal, perhaps by transgenics.
However, in the least squares regression case, all the speakers in the background set are included in the likelihood ratio calculation and their weights are not being altered directly to ensure sparseness.
In this case, temperature shows an additive effect, also called vertical perturbation [66], suggesting that temperature can affect survival or reproduction, thus altering directly the PCGR.
Moreover, it was altered directly during the treatment at stage 8 larvae.
From the perspective of biotechnology, knowing which genes affect metabolite levels is crucial for metabolic engineering since metabolism cannot, whereas gene expression can, be altered directly.
