Sentence examples for alter differentiation of from inspiring English sources

Taken together, these data suggest that our directed differentiation system highly enriches the cardiomyocyte yield, and manipulation of Wnt/β-catenin signaling in this context does not alter differentiation of smooth muscle or endothelial lineages.

Imatinib mesylate, a potent inhibitor of PDGFR-β, has been found either to promote osteoblast differentiation [36] or to suppress proliferation and alter differentiation of human mesenchymal stromal cells, the osteoblast precursors [37].

The additional presence of PPARγ increased percentage of syncytiotrophoblast well above and beyond this DMSO effect; however, rosiglitazone did not further alter differentiation of PPARγ-virus-infected null TS cells as assessed either by morphology or by qRT-PCR (Figure 10C, and data not shown).

Results show that Hdac1 or Hdac2 deficiency altered differentiation of Paneth and goblet secretory cells, which sustain physical and chemical protection barriers, and increased intermediate secretory cell precursor numbers.

An ideal model would realistically recapitulate a marked epidermal hyperproliferation, thickening and altered differentiation of the epidermis, an inflammatory infiltrate that includes T-cells, altered vascularity, and responsiveness to current anti-psoriatic therapies [3] [5].

Thus, the presence of Cx43 in secretory epithelial cells of boars treated with flutamide during fetal and neonatal period may reflect altered differentiation of prostatic epithelium.

Ablation of Ezh2 in the epithelium resulted in perinatal lethality with defective lung development and altered differentiation of multiple lung epithelial lineages.

Expression of the surfactant protein genes Sftp-a and Sftp-c mRNA was reduced in the Sox9Δ/Δ mice, and CC10 mRNA was slightly overexpressed in the mutant trachea, indicating altered differentiation of tracheal epithelium.

Taken together, these results indicate that the enhancing effects of miR-93 and miR-106b on reprogramming do not alter differentiation capacity of induced pluripotent cells and that those derived clones can differentiate into all three germ lines.

Infection at this late time point did not alter differentiation capacity of the cells.

Thus, we speculated whether the lentiviral-mediated overexpression of fl-mrfp-ttksr39 TF driven by the CMV promoter would induce aberrant characteristics or alter differentiation capacity of stem cells.