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The phrase "alter dendritic cells" is correct and usable in written English.
It can be used in scientific or medical contexts, particularly when discussing immunology or cellular biology.
Example: "Researchers are exploring ways to alter dendritic cells to enhance the immune response against cancer."
Alternatives: "modify dendritic cells" or "change dendritic cells".
Exact(1)
Thus, we consider that HDAi alter dendritic cells to a tolerogenic-like phenotype.
Similar(59)
Bedoret, D. et al. Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice.
This appears not to alter dendritic cell migration to draining lymph nodes but is associated with enhanced fluid drainage from peripheral tissues and thus with a hypotensive phenotype.
Thus, the described defects in these mice appear to be due the lack of lymph nodes, the disturbed architecture of the spleen, and deranged chemokine production patterns, rather than to a profoundly altered dendritic cell system.
Histone deacetylase inhibitors have been shown to block Th17 cells induction by altering dendritic cell function [ 27].
In this model, T-cell-dependent autoimmune manifestations are controlled by altered dendritic cell signaling in combination with a defect in B-cell tolerance (Hua et al., 2014).
Probiotics can also modulate immune function by altering dendritic cell [ 59], regulatory T cell [ 60, 61], and T helper cell responses [ 62].
In conclusion, HDAC inhibition ameliorates arthritis in SKG mice, at least in part, by altering dendritic cell function into the tolerogenic phenotype.
55, 56 For example, in murine models of IBD, the helminth Heligmosomoides polygyrus bakeri prevents colitis by altering dendritic cell function.
Melanoma cells are capable of immune subversion within a tumor or draining LN by altering dendritic cell function through the secretion of tumor-derived cytokines [ 72], leading to the generation of suppressive and regulatory T-cells [ 73].
The challenge of influenza virus and pneumococcus altered dendritic cell functions dependent on the time interval between the successive challenge of influenza virus and pneumococcus, as well as the doses of pneumococcus.
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