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This proteolysis by DPP-4-like activity can alter activities of target substrates, including the functional activation and inactivation of bioactive peptides or facilitated degradation of macromolecules by other peptidases [ 14].
Furthermore, TRF2 can alter activities of various DNA metabolic/repair enzymes and the ability of TRF2 to stimulate or inhibit certain activities depends on the nature of the substrate [44], [69], [74], [75], [76].
Currently, AD [ 1, 2] must reach the dementia stage, in which cognitive and noncognitive symptoms significantly alter activities of daily living, to be clinically diagnosed.
Hypothyroid condition did not alter activities of respiratory chain complexes except that it had a strong influence on NADH-DQ oxidoreductase activity which was significantly downregulated.
Conversely, kidney dysfunction may generate a thrombotic milieu indirectly through electrolyte or acid-base abnormalities, which may alter activities of enzymes involved in coagulation.
To this end, we have adopted paradigms in cultured neurons to selectively alter activities of single synapses to study homosynaptic homeostatic response.
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Even mutating both Ser552 and Ser554 to Ala did not alter activity significantly.
Silioxanes identified by GC-MS could alter activity of enzymes through specific or non-specific interactions.
Social defeat may indeed alter activity of these nuclei, but these changes may not be reflected in pCREB or pERK expression in response to a social stimulus.
Our results suggest that elevated CO2 can alter activity and defensive behaviours in a tropical squid.
Exogenously supplied cholesterol does not alter activity levels of StAR-GSV.
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