Exact(2)
Also with the replication threshold, there will generate less copies in the network.
Here we show that TTC4 is a nucleoplasmic protein which interacts with HSP90 and HSP70, and also with the replication protein CDC6.
Similar(58)
Notably, Plk1 has been shown to interact with several DNA-damage-responsive proteins, such as MDC1, 53BP1, and SLX4 (Lowery et al., 2007, Svendsen et al., 2009, van Vugt et al., 2010), and also with the MCM replication complex at stalled replication forks (Song et al., 2011, Trenz et al., 2008, Tsvetkov and Stern, 2005).
The presence of minimal intron is also correlated with the replication timing and chromatin structure of the gene locus, implying specific nuclear positions of these genes.
Like a number of other strains of Wolbachia (Osborne et al. 2009; Walker et al. 2011; Andrews et al. 2012), wMelPop can also interfere with the replication of viruses and other pathogens (Moreira et al. 2009).
Also in agreement with the replication patterns is that large chromosome expression levels appear to gradually decrease with an increased distance from the origin of replication, which is also supported by ori/ter ratios larger than 1.
The reduction of protein and RNA levels was also shown by the treatment of cells in a subgenomic replicon system with 3-hydroxy caruilignan C (3-HCl-C) isolated from Swietenia macrophylla stems, which also increased the replication suppression when combined with IFN-α and protease or polymerase inhibitors (Wu et al., 2012).
Also in the replication studies, DNAm was measured with the 450-k chip.
Locating the regions of the mt genomes associated with the replication origins (ORs, also known as control regions or A+T rich regions) for both "+" and "-" strands can be challenging based on a knowledge of the nucleotide sequence of mt genomes alone.
"Down with the replication bullies!" proclaimed one commenter on Facebook.
It seems that the chromatin state also correlates with replication timing, for example the acetylated form of histone H4, H4K16ac, shows a higher correlation with replication timing than with local transcription [ 23].
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