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However, minimizing such expenditure also represents a challenging task due to the complex and highly-combinatorial nature of the optimization problem.
The rapid step test also represents a challenging cognitive choice-reaction task [ 7, 41].
In our study, M4 was included because it also represents a challenging time, given the reduction in analgesic effect and the manifestation of pain-related behaviour that typically occurs after 24 hours.
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While mixed model analyses have predominantly been used to identify exposure targets for effective prevention and intervention, they also represent a challenging opportunity to develop exposure assessment strategies that are both "cheap" and statistically efficient.
While that shows Mr. McCain's potential general election appeal, it also represents a challenge for him.
The corresponding optimization problem not only embeds the structure of NP-hard problems, but also represents a challenge with a well-structured heuristic approach.
But while Bush and his Pentagon hawks may in the end be wrong in pursuing their National Missile Defence system at risk of established and functioning nuclear treaties, the Taepo Dong II also represents a challenge to the President's critics.
The companies' push also represents a challenge to the defense secretary, Robert M. Gates, who has said he would recommend that President Obama veto any bill that included money for the engine.
It also represents a challenge to sanitary hot water system designers because the amount of hot water as well as the daily profile in which it is consumed impacts significantly on system design.
Measuring the impact of these activities and processes also represents a challenge.
Skill mix also represents a challenge, as the standards vary widely between countries and not many standardized benchmarks exist.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com