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Prospective clinical trials stratifying by PIK3CA genotype will be necessary to determine if the mutation also predicts for increased sensitivity to agents targeting the phosphoinositide 3-kinase pathway.
Whether the newly developed ATM-p53 RT-MLPA assay also predicts for clinical outcome in addition to the molecular status of ATM and/or TP53 needs to be further evaluated in large clinical prospective studies.
In other words, the regression model predicts (in trial 6) for an MCI individual the same performance as to a normal individual with 15 years more than them; it also predicts for an AD individual the same performance as to a normal individual with 22.7 years more than them.
Activating BRAF V600E mutations are also known to occur in subsets of thyroid and colon carcinomas (Davies et al, 2002), and similar to melanoma, the presence of the mutation also predicts for sensitivity to MEK inhibition (Solit et al, 2006; Leboeuf et al, 2008).
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Notably, for approximately 25% of the predicted targets, these functional gene orthologs were also predicted for human/mouse/rat using the PicTar target prediction program [ 21].
When the sharp rise in sales of rosé wine were announced at the last Vinexpo and a worldwide increase also predicted for the next few years, I decided to check out my local Cave de vin co-operative where I regularly buy my five-litre "bag in the box Côtes de Provence".
Showers are also predicted for Saturday and Sunday.
Markstein numbers are also predicted for all these fuels.
The RT of sphingo- and glycerolipid species was also predicted for our LC condition.
A similar effect is also predicted for initial martensitic lath width at temperatures below 500 °C.
The heat exchange rates were also predicted for three months using the numerical analysis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com