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Dr Fantin and Dr Leder also observed a marked decline in tumour growth rates.
We also observed a marked up-regulation of POSTN, a protein involved in proper ECM synthesis [25] and in the hypertrophic response following myocardial infarction [26].
Similarly, we have also observed a marked increase in spontaneous DNA damage foci formation shown by co-localization of DNA damage markers pH2AX and 53BP1 in the nucleus of proliferating and differentiating Chk1+/− erythroblasts during erythropoiesis.
In a subgroup of the present study population with urinary catecholamine excretion measured at baseline, we also observed a marked increase in adrenaline excretion and some increase in the excretion of noradrenaline with increasing coffee intake.
We also observed a marked increase in CTLA-4 expression among T cells from infected mice.
We also observed a marked down-regulation of nephrin expression in cultured podocytes after exposure to burns septic ARF group plasma.
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We also observe a marked overlap between HHsearch and domain assignments using SUPERFAMILY database (89 cases).
We also observed a substantial increase in SUMO-2/3 conjugation in HEK293 cells and a corresponding marked decrease in SENP3 levels immediately after OGD (Supplementary Figure 1B).
Also we observed a marked decrease in both cell lines undergoing proinflammatory stimulation.
Noteworthy, in contrast to MTT results, we observed a marked decrease of cell growth also for SH-SY5Y and KELLY cells.
Had science failed utterly, we would have observed a marked increase in cancer deaths.
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Justyna Jupowicz-Kozak
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