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Similarly, pre-mRNA 3′-end processing in yeast also involves a large protein machinery.
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It also involves a larger scale of resource mobilization, and the resources the service center obtains are of better quality.
That case, which also involved a large recall, was a severe financial blow to Firestone and was one reason it was acquired in 1988 by Bridgestone.
This program also involved a large number of participants from governmental organizations, non-governmental organizations, academicians, patient groups and health care providers.
The study also involved a large cohort composed entirely of women in Africa, a population severely affected by the HIV-1 epidemic but in whom minimal longitudinal CD4 response data (after HAART initiation) are available.
Only a small percentage of tumor cells in this system are infected by the adenovirus, so while the anti-tumor growth may be mediated by apoptosis, it is likely to also involve a large bystander effect, and perhaps anti-angiogenesis mechanisms [ 64].
However, unlike pairwise interactions among particles that typically govern solid-state physics systems, interactions among humans often involve group interactions, and they also involve a larger number of possible states even for the most simplified description of reality.
Also, involving a larger group of stakeholders introduces new demands on founding teams.
The National Authority for Medicolegal Affairs decided that written informed consent from the women was not required as the practice of the trial was considered routine and it also involved a very large number of women.
The penalties on Germany's largest bank also involved a guilty plea to the Department of Justice (DoJ) in the US and a deferred prosecution agreement.
Other information theoretic methods that infer biological network connectivity from data sets with larger sample sizes[14], also involve a considerable effort to remove effects that are dominated by global correlations such as the use of the data-processing inequality[15].
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