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To determine whether the conservative HR is also implicated in the repair of Top2-mediated damage, we analyzed several end points.
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The unique phosphodiesterase activity of TDP1 has also been implicated in the repair of a variety of oxidative 3′-termini, such as 3′-phosphoglycolate (Inamdar et al, 2002; Interthal et al, 2005b; Zhou et al, 2005, 2009).
p53 is also implicated in the checkpoint of cell-cycle progression in combination with DNA repair and/or induction of apoptosis.
He was also implicated in the murder of his former wife.
These structures are also implicated in the capacity of resilience [14].
LXRs are also implicated in the control of steroid metabolism.
DNA methylation is also implicated in the biology of CLL.
They are also implicated in the process of ageing.
The BRIP1 gene is also implicated in the Fanconi anemia (FA DNAA repair pathway, a pathway responsible for repairing DSBs in DNA to prevent other genetic conditions [40].
Other important EMT signaling pathways are also implicated in the transformation and maintenance of CSCs.
Some of these proteins were also shown to be implicated in the repair of membrane tears of muscle fibres like annexins which are fusogenic proteins with affinity for membrane lipids and phosphoinositides [14], [29] or MG53, a protein implicated in vesicular trafficking [12].
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