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KC was PI of the study and planned, organized, and supervised animal experiments, hormone stimulation of prostate, the carcinogenesis study, and evaluation of morphological alterations in various prostate lobes; KC also evaluated the data and wrote the manuscript, which all authors have read and approved.
Since the various recombination detection methods that are available may yield different results, we also evaluated the data with the InSites algorithm (http://indra.mullins.microbiol.washington.edu/cgi-bin/InSites/index.cgi), which has been used to detect recombinant sequences by visual inspection of shared nucleotide sites in an alignment [39].
HF wrote the first draft and also evaluated the data.
We also evaluated the data base available from a previous review of community-based interventions to address perinatal outcomes [ 51].
In addition, to the analysis by geNorm we also evaluated the data with NormFinder algorithm (Table 4).
To assess potential bias, we also evaluated the data of the 43 patients who were lost to follow-up.
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We also evaluated the CEA data in the TCH dataset.
We also evaluated the CN data of erbB2 by real-time PCR using the ROC curves, which provide an analysis of the sensitivity and specificity of the assay.
We also evaluated the expression data of CREB5, PTPRB and COL4A3 from Oncomine [ 9], indicating that CREB5, PTPRB and COL4A3 were significantly lower in carcinoid than normal lung tissues (Additional file 1: Figure S1), which was accordant to the results of the DASL and RNA-seq datasets.
To exclude any loss of information introduced by spike detection, we also evaluated the raw yaw torque data series.
We also evaluated the effect of missing data for the statistical models estimated.
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