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In such cases, it is also essential to determine the observer reliability.
Once established the conceptual difference between these terms, it is also essential to determine the instruments suitable to assess each of them in diabetes research.
It is also essential to determine how the social behavioral data should be collected (in real-time or through surveys), archived for easy access, retrieved, and translated into model parameters.
It is also essential to determine whether the frequency or distribution of ALDH+ putative stem cells in histologically normal breast tissue is related to risk factors for breast cancer.
While gaining data on overall SBMU as a single construct is important, it is also essential to determine the different types of SBMU being utilised and for what activities, because there is evidence of their differential effects on health (see [ 33]).
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It's also essential to check for: Worn valve stems.
Molecular biomarkers are also absolutely essential to determine proof of concept for modulation of the desired target, and to help determine what is the optimal dose and administration schedule.
Finally, it will also be essential to determine whether patients who develop resistance to cyclin-dependent-kinase inhibitors are responsive to BET bromodomain inhibition.
Moreover, in most practical applications, the heat transfer fluid is not stationary [3], and consequently, the analysis of the rheological properties is also essential to appropriately determine the increments on the average heat transfer coefficient of the flowing system, which generally increases with the concentration of nanoparticles as well as with the Reynolds number [2].
Owing to the marked radioprotective effect on normal tissue, it was essential to determine whether these agents could also exert a tumour protection after irradiation.
In the near future it will be essential to determine whether less toxic combinatory doses are also effective in patients.
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