The phrase "also be species" is not correct in English and seems incomplete.
It may be intended to refer to the inclusion of additional species in a discussion or context.
Example: "In this ecosystem, there can also be species that thrive in extreme conditions."
Alternatives: "may also include species" or "can also refer to species".
The effects of folic acid may also be species specific, she says.
The R- and S-isomers may differ in nonspecific binding, metabolic stability and distribution volumes, and these differences can also be species dependent.
This finding suggests that there may also be species differences in the regulation of cell-cell adhesion, which could be due in part to the differential involvement of Dia downstream of Rho, or to other Rho GTPases [21].
The site of rapid glucocorticoid feedback may also be species specific.
Furthermore, there might also be species differences in defense capacities (Knobloch et al. 2008).
Our results correlate with that and suggest that this bias could also be species specific among bacteria and eukaryotes.
There may also be species-specific differences in terms of antioxidant defenses [80], although the studies cited above include both mammals and fishes.
Secondly, since MODY is known to be a disorder of haploinsufficiency [13], [14], we cannot rule out the possibility that there may also be species-specific differences in the dosage of the HNF1A, HNF1B and HNF4A gene products that are required for full function.
However, it is known that different gene isoforms may play different, and even antagonistic, functional roles that can also be species-specific [ 19].
Reviewer 2 By concentrating on catalytic function in their discussions of evolutionary pressure, the authors may be missing the fact that an increasing number of enzymes are now recognized to be multifunctional (sometimes also called "moonlighting") proteins, with alternative, distinct, functions that may also be species-specific.
