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PEG 5 -BP-USPIOs can also be labeled using a radiolabeled-BPEG 5 -BP-USPIOsion with single PEG 5 -BP-USPIOscanputed tomogralso (SPECT), and thus affording dual-modality contrast.

Next-generation somatostatin analogs have been developed using the chelator DOTA rather than diethylenetriaminepentacetate (DTPA), and these molecules can also be labeled using positron-emitting radionuclides, such as Ga (Table 1).

PEG 5 -BP-USPIOs can also be labeled using a radiolabeled BPEG 5 -BP-USPIOs, that allows tracking of the NPEG 5 -BP-USPIOsmaging with high sensitivity and quantificanion calsoilities.

The first, a 4-fluorobenzylamine conjugate of 2-nitroimidazole (PK-110), was designed so that it could also be labeled with the F-18 and used for positron emission tomographic imaging of hypoxia.

IMP466 also was labeled in solution using a higher dose of peptide in a two-step, one-pot solution process that afforded the Al18F-IMP466 in 97% decay-corrected yield after HPLC purification [29, 30].

In addition to evaluation of biodistribution by initially in vitro 99mTc radiolabeled replication deficient Ads, we expect virions containing the pIX-metallothionein fusion proteins can also be potentially labeled using 188Re [33].

For comparison, 5F7 Nanobody was also labeled using the residualizing radioiodination agent N-succinimidyl 4-guanidinomethyl-3- 125 I-iodobenzoate ((125)I-SGMIB).

As a relative comparison, wild-type tissue was also labeled using the GFP antibody (Fig. 2E).

Seventy-three PCa specimens obtained by radical prostatectomy performed at the University of Rochester Medical Center were also immunohistochemically labeled, using the specific primary antibodies to snail, CCL2, and pSTAT3.

Reference DNA, prepared from single diploid cumulus cell, was also amplified and labeled using Green 496-dUTP (Enzo Life Sciences) fluorescent dye.

We speculated that biotin labeling could also be used to label other cell types.