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In excess, these nutrients are also a primary contributor to algae blooms and so-called "dead zones," large areas with such low levels of oxygen that animals can't survive.
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However, this would also seem unlikely to be a primary contributor as measured rates of mRNA transcriptional error are 1 - 2 orders of magnitude lower than that observed in these studies [ 25, 26].
Legions of critics have also attacked the central bank as a primary contributor to the economic crisis, charging that its lax monetary policy allowed the housing bubble to inflate.
From a clinical point of view, our findings highlight the need of a more strict control of glycemic levels, considering also the fact that hyperglycemia represents a primary contributor to the reduced number and impaired function of EPCs in diabetes [ 18, 30].
The relatively high rate of preterm birth observed in Kaniyambadi also requires attention; preterm birth is increasingly being recognized as a primary contributor to perinatal death in less industrialized countries [ 39].
The calpain susceptibilities of SMNΔ7 and SMNΔ7+EMLA proteins were also similar to that of WT (Figs. 4A,B, and S5), indicating that calpain cleavage is not a primary contributor to the instability of SMNΔ7.
With sustainability central to this year's theme, the event also directed attention to the fact that our global food system is highly fossil fuel dependent and is a primary contributor to greenhouse gas emissions.
He went on, "I would not agree that it's a primary contributor to the global warming that we see.
Diabetes is increasingly prevalent and a primary contributor to the major causes of disability and death.
Therefore, the topographic effect was a primary contributor to the very small-scale variation in heat flow in this region.
Speed is a primary contributor to crash frequencies and increased severity with over 30% of traffic fatalities attributed to speed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com