The strategy (which is by now standard) consists in starting with the energy (E t)) and modifying it by adding new adequate terms (functionals) which may be estimated below and above by similar terms already existing in the expression of the energy (leading to the equivalence of both functionals) and whose derivatives provide us with the missing terms in the energy after differentiation.
One can speculate that Cd might interfere with already existing sex-specific gene expression, or alternatively it causes sex-specific DNA methylation for genes that should not differ between the sexes.
Because of the manageable number of differentially expressed genes, we crosschecked their expression to already existing microarray data (see additional file 1).
However, it is uncertain whether all these factors including maternal arterial stiffness are the cause or the phenotypic expression of the already existing underlying pathophysiological mechanisms of PE.
If there is a concept for that expression, the common sense and inferentialist relations, already existing in the knowledge base, are retrieved to be validated by the user.
To further establish their possible involvement in development and abiotic stresses, we have analyzed the expression of genes encoding CDCPs using MPSS database and already existing Arabidopsis microarray database.
By Stern's lights, all of the other mega-towers springing up around Manhattan — be it Bjarke Ingels's Two World Trade Center, or Jean Nouvel's 53W53, or SHoP's 111 West 57th — are simply expressions of one or the other aesthetic tendency already existing within architecture, playing themselves out in a cyclical return.
The accumulation of gene expression studies has created a situation where one can pose new questions about the co-expression and functional role of genes by integrating the already existing data (Wren, 2009).
It is likely that the Btg2 expression in maturing granule cells might be linked to integration into the already existing neuronal networks and is subject to the inputs of various neurotransmitter systems during the maturation.
We believe the systems approach to rationally choose promoters, transactivators and inducer molecules, to obtain desired and predefined genetic expression dynamics and control profiles, will significantly advance the design of new regulatory circuits as well as improving already existing ones.
