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The phrase "already a difference" is correct and usable in written English.
It can be used to indicate that a change or distinction has been made or observed at an earlier point in time.
Example: "After implementing the new strategy, there was already a difference in team productivity."
Alternatives: "there is already a change" or "a difference is already evident."
Exact(2)
Jones conducted a session on Tuesday with the 10 squad players not involved in his match-day 23 and estimates there is already a difference in fitness between them and those who have spent longer under his more intense regime.
Although we did not see a change in numbers of OPC undergoing apoptosis at 2 weeks after lesion between control and treated groups when there is already a difference in OPC numbers, we cannot exclude that death and clearance of OPCs may occur very fast and before this time point.
Similar(58)
I would have liked them to have done so without me having to take action but it has already made a difference already.
Passengers, she said, are already seeing a difference because JetBlue and Delta have voluntarily redistributed some flights to different times.
It's already making a difference.
It's already made a difference for the softball team.
Our pressure, and practical help, are already making a difference.
"It has already made a difference," she says.
Some activists believe their campaigns have already made a difference.
Syndergaard said he could already feel a difference.
Marotti said he had already seen a difference.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com