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The HGL surface maintained cells in a less-advanced differentiation state (as determined by ALP data), whereas the CNWs promoted the later stage of the cell differentiation process, as marked by the cellular mineral production (demonstrated by the calcium data).
Expression of RunX2 and BMP2 substantiated the ALP data.
The ALP data were described as nmol/15 min/mg protein.
As the CA19-9, bilirubin, CRP and ALP data were skewed, logarithmic transformation was applied before carrying out regression analyses.
Eastern Cooperative Oncology Group performance status (ECOG PS) assessment, serum haemoglobin (Hb) and serum alkaline phosphatase (ALP) data were collected prospectively, but not available for all participants.
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PI3 kinase and PKC inhibitors had no significant effects on ALP activity (data not shown).
Ten days after treatment, direct and simultaneous transfer of the BMP-2 and BMP-7 genes induced higher ALP activity (data not shown), and more intense calcification than did the transfer of either gene alone.
This enabled the differentiation/mineralization data (ALP and calcium) to be adjusted according to the number of cells attached to each test substrate and TCPS control at day 25.
In this paper, we present an approach for designing homogeneous zones optimising the spatial distribution of an area-level exposure, active living potential (ALP), based on data collected in Montreal, Canada.
HZ, LO, FGG, MC, CJ, MMA, ALP analyzed the data.
Interestingly, Ereg overexpression had no effect on the expression of Alp and OC (data not shown).
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