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In the real space images, the channeling effect along aligned atomic columns is visible in all simulations [41].
We show that multilayered and elongated CMs could be organized at high density along aligned nanofibers in a simple one-step seeding process, resulting in upregulated cardiac biomarkers and enhanced cardiac functions.
DRG neurons plated on top of oriented astrocyte monolayers exhibited directional outgrowth along aligned astrocytes, demonstrating that purely biological cues provided by the oriented astrocytes were sufficient to provide guidance cues.
The rapid ability of multicellular tissues to physically remodel their matrix enables their constituent cells to migrate efficiently along aligned fibers and to quickly change their direction according to other microenvironmental cues, which is important for both normal and disease processes.
As a result, cells are constrained to move along aligned collagen fibers.
Axons regenerate along aligned Schwann cells called bands of Büngner, which form a permissive environment (Allodi et al., 2012).
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Rabbit ligament fibroblast cell attachment and infiltration study conducted on the scaffolds showed cell elongation along the aligned fibers, which would be advantageous in the need to align cells along the direction of force in native ligament environment.
Most of the attached MSCs elongated along the aligned fibers.
The secondary injection along the aligned surfaces joins the two halves into the final hollow part.
Importantly, co-seeded neurons extended neurites directly along the aligned astrocytic bundles, demonstrating permissive cues for neurite extension.
Assume axis x 2 as the direction along the aligned nanotube.
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