Left alone, that cycle could repeat itself.
If you wander among the more than 300,000 words — the equivalent of a few novels — that the Republican candidates have uttered in the debates alone this cycle, you will find more than the habitual chest-thumping, flag-waving, support-our-troops fare on the question of America in the world.
Using this alternative approach, each signature still added significantly to the risk prediction using the clinical covariates alone (Cell cycle P = 0.002; cell death P = 0.05; cell growth P = 0.04).
This then suggests that pore lifetimes are sufficient to allow partial solute leakage (fractional loss, ∼1/e) required to relax membrane tension and promote pore closure through effusion alone per cycle.
In the simulations performed for this study, selection on marker scores alone in cycle 0 led to greater genetic gain than selection on phenotypic values or GEBV-phenotype indices (results not shown), and therefore all selections made in cycle 0 were based on marker scores alone.
The premenopausal women were enrolled in the DBCG82 b protocol and were randomly assigned to receive either radiotherapy plus CMF (cyclophosfamide, methotrexate and fluorouracil) chemotherapy (eight cycles) or to CMF chemotherapy alone (nine cycles) [ 18].
Briefly, from 1990 to 1999 in Trial VIII, 1,063 pre- and peri-menopausal women with node-negative early breast cancer were randomly assigned to endocrine therapy with 24 months of goserelin alone, six cycles of chemotherapy with classical cyclophosphamide, methotrexate and 5-fluorouracil (CMF) or a sequence of 6 cycles of CMF followed by 18 months of goserelin.
The patient received temozolomide chemotherapy and radiotherapy followed by chemotherapy alone (6 cycles).
The GELA LNH 93 4 trial [ 35] randomized 576 patients older than 60 with ALNHL and without age-adjusted IPI risk factors [ 36] to receive 4 cycles of CHOP alone or 4 cycles of CHOP plus 40 Gy IFRT.
This patient received trastuzumab plus capecitabine and cisplatin as initial therapy and continued maintenance therapy with trastuzumab alone for 47 cycles after completing 6 cycles of chemotherapy [ 47].
