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However, for %iAs the multivariate analyses showed only an association with sex and an almost significant association with a polymorphism in the MTHFR gene.
However, in patients with type 2 diabetes (p=0.073), an almost significant association was detected, and in participants from the general population with self-reported diabetes, a significant association was identified (p=0.04).
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Among migrants, age showed almost significant associations with HRQoL (p = 0.07).
Most significant associations were strengthened upon adjustment.
Little is known about the interaction between HIF-1 and ER, but an almost significant positive association was found in endometrial cancer [ 30] but not in breast cancer [ 11, 31].
And a direct and almost statistically significant association was also found with the "years of practising prostitution" ("p value": 0.072; OR: 1.13; 95%CI 0.99 1.29).
There were almost no significant associations between any pre-admissions measure and the year 5 exam results.
If it is true, it is curious that MRI dense volume showed almost no significant associations with any of the tested anthropometric or hormonal factors.
We only considered P < 0.01 to be significant in view of the multiple factors evaluated, and almost all significant associations had a P < 0.0001, reflecting the large sample size.
Third, a large number of statistical tests have been performed, which may induce false positive results due to multiple testing; however, almost all significant associations remained after adjustment for multiple comparisons.
Also, Gilbody et al. [ 31] and Jönsson et al. [ 33] in their meta-analysis on BD reported almost significant or borderline significant association with MTHFR C677T, and the frequency of the T allele was increased among BD patients [ 31, 33].
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